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Individual endothelial cells arejoined by tight junctions that restrict passage of molecules fromthe lumen into underlying tissue, b. Moreover, in the absence of PD dif-ferences between animal species, it is expected that similarresponses will be produced at equivalent tissue exposuresregardless of species, exposure route, or experimentalregimen. David eventually received a satisfyinganswer to his earlier question: What kind of fucking life is that? It seems itwas a surprisingly good one.

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